Plasma Processes and Polymers: Article on surface functionalisation of microfluidic chips
Surface Functionalisation of Microfluidic Chips
Feature Article: Interesting article on plasma surface functionalisation of microfluidic chips.
Surface Functionalization by Plasma Treatment and Click Chemistry of a New Family of Fluorinated Polymeric Materials for Microfluidic Chips
Yoann Ladner1,2,3,4, Fanny D’Orlyé1,2,3,4, Camille Perréard1,2,3,4, Bradley Da Silva5,Cédric Guyon5, Michael Tatoulian5, Sophie Griveau1,2,3,4, Fethi Bedioui1,2,3,4 and Anne Varenne1,2,3,4,* Version of Record online: 17 APR 2014 DOI: 10.1002/ppap.201300120 © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
The surface modification of a new family of microfluidic chip materials based on a commercial fluorinated thermoplastic polymer (Dyneon THV) was performed for the first time. This modification was done following a four steps approach, involving first the cleaning of surface and then the bromination of the surface by plasma treatment, followed by two successive chemical reactions involving click reaction to graft chemical functions at the polymer surface. It was demonstrated by a thorough surface analysis of Dyneon (XPS, FTIR-ATR) that surface oxidation allowed increasing the hydrophilicity of the THV surface and brominated film deposition by plasma treatment allowed incorporation of different functional groups on the Dyneon surface through click chemistry.
Dyneon THV is a new class of material that is well suited for droplet and organic solvent microfluidics.  This thermoplastic fluoropolymer is a terpolymer of tetrafluoroethylene (F2 C55CF 2), hexafluoro propylene (F2 C55CF—CF 3) and vinylidene (H2 C55CF 2). It has a very low surface energy, a hydrophobic character and a high resistance to chemicals. Furthermore, its low melting temperature (TM 165 8C) makes its use in microchip fabrication processes simple and fast. However, this emerging substrate lacks chemical reactivity; indeed the aliphatic carbon and fluorine atoms that constitute the THV backbone make difficult the surface functionalization of this substrate by conventional chemical methods. To the best of our knowledge, no studies related to the surface modification of THV are referenced so far in the literature. In this study, the surface activation and functionalization of THV substrate by plasma processes is reported for the first time following previously reported approaches developed for other materials. [2–10]
To read the remainder of the article please click the link below;